[Virology Journal] Scientists examined the impact of magnesium supplementation on clinical outcomes and biochemical factors among hospitalized patients with COVID-19.

[Journal Of Health Population And Nutrition] Investigators analyzed the correlation between blood glucose control and the severity of COVID-19 infection in patients with diabetes.

[International Journal Of Biological Macromolecules] An immunoinformatics method was applied to design a multi-epitope vaccine against the hepatitis C virus (HCV). The best B- and T-cell epitopes from conserved regions of the E2 protein of seven HCV genotypes were joined with the appropriate linkers to design a multi-epitope vaccine.

[Acta Pharmacologica Sinica] Researchers performed a high-throughput screening of FDA-approved compound library in the J-Lat A2 cell line to discover more efficacious latency-promoting agents. They discovered ripretinib being an LPA candidate, which was validated and observed to hinder proviral activation in cell models harboring latent infections, as well as CD4+ T cells derived from infected patients.

[Periodontology 2000] Investigators focus on three major aspects of oncoviruses' role in cancer development. They discuss geographic distribution, revealing that seven oncoviruses cause 20% of all human cancers worldwide.

[Aids Research And Therapy] The authors highlight the potential direct and indirect role that HIV infection may play in the development of erythema multiforme and the clinical dilemma that arises in the management of HIV-infected patients with this condition.

[CNN Health] The World Health Organization is opening up the definition of airborne pathogens – such as Covid-19, influenza and measles – to include when respiratory droplets spread through the air and when they land on a person, regardless of the size of the droplet.

[Nature Communications] The authors showed that the hyperactivation of Janus kinase 2 by the V617F mutation phosphorylated tyrosine residues in coactivator-associated arginine methyltransferase 1 (CARM1), an important target in hematologic malignancies, increasing its methyltransferase activity and altering its target specificity.

[Nature Communications] Researchers investigated the clinical consequences of a genetic predisposition toward lower white blood cell (WBC) counts among 89,559 biobank participants from tertiary care centers using a polygenic score for WBC count comprising single nucleotide polymorphisms not associated with disease.

[EMBO Journal] Investigators reported that expression of tricarboxylic acid cycle enzyme succinate-CoA ligase SUCLG1 strongly correlated with electron transport chain genes across various TCGA cancer transcriptomes.

[Proceedings Of The National Academy Of Sciences Of The United States Of America] Researchers defined the genomic binding sites of PML::RARA in primary mouse and human hematopoietic progenitor cells with V5-tagged PML::RARA, using anti-V5-PML::RARA chromatin immunoprecipitation sequencing and CUT&RUN approaches.

[Blood Advances] In this retrospective study, allogeneic blood and marrow transplantation (alloBMT) recipients age 60 and older with lymphoid malignancies were included. Among 97 consecutive patients who received alloBMT between 2017 and 2022, cloal hematopoiesis was detected in 60.