[Insider Precision Medicine] Researchers at the University of California, San Francisco (UCSF) have begun enrollment for a clinical trial that uses a new, powerful version of CAR T as a potential therapy for glioblastoma, the most common and deadly adult brain cancer.

[University of Toronto] The University of Toronto (U of T) is collaborating with the University Health Network, the Hospital for Sick Children, and Sunnybrook Research Institute on a new program that aims to leverage the expertise of entrepreneurs and business leaders to advance commercialization of emerging medical technologies and regenerative medicine research.

[Scientific Reports] Researchers developed a scaffold-free, 3D tendon culture system using mouse tendon cells in a differentially adherent growth channel.

[Business Insider] Healthcare innovator Dr. David Greene announced the establishment of the esteemed Dr. David Greene Scholarship for Medical Students, aimed at fostering excellence and innovation in the medical community. This scholarship, valued at $1,000, presents a unique chance for undergraduate students to further their medical ambitions.

[Advanced Materials] Scientists design an ultra-strong ligand, L-histidine–L-histidine, specifically targeting sialylated glycans on the surface of circulating tumor cells.

[Stroke] Investigators explored the possibilities of ependymal repair in GMH/PHH using a combination of neural stem cells, ependymal progenitors, and mesenchymal stem cells.

[Pigment Cell & Melanoma Research] Using a cell enrichment strategy to isolate KIT+/CD45− cells from the telogen skin of adult female C57BL/6J mice, investigators evaluated the transcriptional landscape of quiescent melanocyte stem cells at high resolution.

[PLOS One] A serum-derived phospholipid, lysophosphatidic acid (LPA), was identified as an important biologic inhibitor of RIPK4. LPA functioned by inhibiting the transcription of RIPK4 mRNA.

[European Journal Of Clinical Investigation] Scientists investigated how ECM composition modulated CD8+ T cell function in undifferentiated pleomorphic sarcoma, an immunologically active desmoplastic tumor.

[Advanced Materials] Bottlebrush polymers were synthesized and crosslinked to form poly(ethylene glycol)-based hydrogels and used to study how strain-stiffening behavior affects human MSCs.

[Journal Of Cellular And Molecular Medicine] Scientists investigated the anti-acute myelogenous leukemia (AML) activity of bortezomib, emphasizing its anti-leukemic stem cells potential, using KG-1a cells, an AML cell line with stem-like properties.

[Cell Reports Medicine] The authors performed ex vivo drug screening of CML CD34+ leukemic stem/progenitor cells using 100 single drugs and tyrosine kinase inhibitor-drug combinations and identify sensitivities to Wee1, MDM2, and BCL2 inhibitors.