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TOP STORIES

Harnessing the Brain's Own Ability for Repair
Neuroscientists at Sydney's Garvan Institute of Medical Research have shown that nerve cells in the brain produce an anti-inflammatory molecule that allows the brain to repair itself.

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SCIENCE

Fluorescent Genetically Modified Monkeys 'Could Help Find Parkinson's Cure'
Scientists have genetically modified marmoset monkeys with a fluorescent protein that under ultra violet light makes them glow a vivid green, but are able to pass on their unique ability to their offspring.

Ceregene Presents Additional Clinical Data from Phase 2 Trial of CERE-120 for Parkinson's Disease
Ceregene, Inc. today reported additional clinical data from a double-blind, controlled Phase 2 trial of CERE-120 in 58 patients with advanced Parkinson's disease.

Capturing the Birth of a Synapse
Researchers have identified the locking mechanism that allows some neurons to form synapses to pass along essential information.

Defining Neurological Deficits in Pediatric MS Patients
A study by researchers in UB's Pediatric Multiple Sclerosis Center of Excellence has produced the first examination of deficits in pediatric patients with demyelinating disorders compared to healthy children, using a new battery of neuropsychological tests for pediatric multiple sclerosis.

Caltech Scientists Reveal How Neuronal Activity is Timed in Brain's Memory-Making Circuits
A new study conducted by researchers argues that the long-held assumption of Theta oscillations as a type of prominent brain rhythm that orchestrates neuronal activity needs to be revised.

Most Common Brain Cancer May Originate in Neural Stem Cells
University of Michigan scientists have found that a deficiency in a key tumor suppressor gene in the brain leads to the most common type of adult brain cancer.

Protein Linked to Mental Retardation is Found to Control Synapse Maturation, Plasticity
A team of neuroscientists at Cold Spring Harbor Laboratory has demonstrated the mechanism by which a signaling protein found throughout the brain controls the maturation and strength of excitatory synapses, the tiny gaps across which the majority of neurons communicate.

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ABSTRACTS

A General Model of Synaptic Transmission and Short-Term Plasticity
This study offers a comprehensive model of presynaptic processes, encompassing mobilization of reserve vesicles, priming of docked vesicles, their association with Ca2+ channels, and refractoriness of release sites. (Neuron)

Numb-mediated Neurite Outgrowth is Isoform-dependent, and Requires Activation of Voltage-dependent Calcium Channels
This paper reports that the neural cells expressing Numb isoforms with short phosphotyrosine-binding domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel inhibitor or by Ca2+ chelator. (Cellular Neuroscience)

A General Model of Synaptic Transmission and Short-Term Plasticity
This study offers a comprehensive model of presynaptic processes, encompassing mobilization of reserve vesicles, priming of docked vesicles, their association with Ca2+ channels, and refractoriness of release sites, while accounting for data on presynaptic buffers governing Ca2+ diffusion. (Neuron)

High-dose Corticosteroids After Spinal Cord Injury Reduce Neural Progenitor Cell Proliferation
The researchers assessed whether a clinical dose of the anti-inflammatory drug methylprednisolone (MP) given to adult mice acutely after spinal cord injury (SCI) influences spinal cord or hippocampal progenitor cells.

Cyclin-dependent Kinase 5 Activator p35 Over-expression and Amyloid Beta Synergism Increase Apoptosis in Cultured Neuronal Cells
In this study the researchers used a tetracycline transactivator system to increase p35/GFP in neuronal cells, an activator associated with Alzheimer's disease.

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INDUSTRY

Commercial Partnership with STEMCELL Technologies Inc
ENKAM Pharmaceuticals A/S is pleased to announce that it has signed a licensing and development agreement with STEMCELL Technologies Inc, which is a leader in specialty cell culture media, cell separation products and ancillary reagents for life science research.

Cellular Dynamics Licenses Key Patent Portfolio Surrounding Cardiovascular Progenitor Cells
Further broadening its leading IP position, Cellular Dynamics International recently announced that it has exclusively licensed a key patent portfolio for the differentiation of stem cells into human cardiovascular progenitor cells.

£4m Grant for Stem Cell Research
A £4 million British Government grant has been awarded to scientists conducting research into stem cell treatments for broken bones.



POLICY

Maryland Stem Cell Research Commission Public Meeting Notice

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