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ABSTRACTS
A General Model of Synaptic Transmission and Short-Term Plasticity
This study offers a comprehensive model of presynaptic processes, encompassing mobilization of reserve vesicles, priming of docked vesicles, their association with Ca2+ channels, and refractoriness of release sites. (Neuron)
Numb-mediated Neurite Outgrowth is Isoform-dependent, and Requires Activation of Voltage-dependent Calcium Channels
This paper reports that the neural cells expressing Numb isoforms with short phosphotyrosine-binding domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel inhibitor or by Ca2+ chelator. (Cellular Neuroscience)
A General Model of Synaptic Transmission and Short-Term Plasticity
This study offers a comprehensive model of presynaptic processes, encompassing mobilization of reserve vesicles, priming of docked vesicles, their association with Ca2+ channels, and refractoriness of release sites, while accounting for data on presynaptic buffers governing Ca2+ diffusion. (Neuron)
High-dose Corticosteroids After Spinal Cord Injury Reduce Neural Progenitor Cell Proliferation
The researchers assessed whether a clinical dose of the anti-inflammatory drug methylprednisolone (MP) given to adult mice acutely after spinal cord injury (SCI) influences spinal cord or hippocampal progenitor cells.
Cyclin-dependent Kinase 5 Activator p35 Over-expression and Amyloid Beta Synergism Increase Apoptosis in Cultured Neuronal Cells
In this study the researchers used a tetracycline transactivator system to increase p35/GFP in neuronal cells, an activator associated with Alzheimer's disease.

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