Cancer-Fighting Drugs Delivered Right to the Tumor
An encapsulation breakthrough using polymeric microcapsules containing human mesenchymal stem cells (MSCs), may enable doctors to deliver anti-cancer drugs directly to tumors over extended periods of time, while preventing the systemic side effects of chemotherapy and other current cancer treatments. [Technion-Israel Institute of Technology, New York]

Bone Repair 'Breakthrough' at Hadassah
A team has managed for the first time in the world to separate platelets and adult stem cells from the blood and bone marrow of patients with fractures and inject them - causing the bones to meld in a quarter to third of the time it usually takes to repair bones, and repairing some breaks that without the therapy would fail to heal at all. [Jerusalem's Hadassah University Medical Center, Jerusalem]

CURRENT PUBLICATIONS

Efficacy of Bone Marrow-derived Mesenchymal Stem Cells in the Treatment for Sclerodermatous Chronic Graft-versus-Host Disease: A Clinical Report of Four Patients
Results are strongly in favor of the idea that the mesenchymal stem cell treatment for sclerodermatous chronic graft-versus-host disease (ScGVHD) patients is therapeutically practical without any detectable side effects, which may provide a new insight into the matter of treating ScGVHD clinically, thus will greatly increase the survival rate of leukemia after allogeneic bone marrow transplantation. [Biol Blood Marrow Transplant]

Mesenchymal Stem Cells Derived from Human Gingiva Are Capable of Immunomodulatory Functions and Ameliorate Inflammation-Related Tissue Destruction in Experimental Coliti
Gingiva-derived mesenchymal stem cells (GMSCs) can function as an immunomodulatory and anti-inflammatory component of the immune system in vivo and is a promising cell source for cell-based treatment in experimental inflammatory diseases. [J Immunol]

Encapsulated Human Mesenchymal Stem Cells: A Unique Hypoimmunogenic Platform for Long-Term Cellular Therapy
Mesenchymal stem cells (MSCs) are known to be hypoimmunogenic and can be genetically modified to express a variety of therapeutic factors. Researchers have designed alginate-PLL microcapsules that can encapsulate human MSCs for extended periods, as demonstrated by fluorescence and H3-thymidine assays. [FASEB J]

Efficient Expansion of Mesenchymal Stromal Cells from Umbilical Cord under Low Serum Conditions
Umbilical cord is a convenient, efficient source of Mesenchymal stromal cells that can be expanded under low serum conditions for application on future studies of tissue regeneration and immunosuppression. [Cytotherapy]

Airway Delivery of Mesenchymal Stem Cells Prevents Arrested Alveolar Growth in Neonatal Lung Injury in Rats
Bone marrow-derived mesenchymal stem cells prevent arrested alveolar and vascular growth in part through paracrine activity. Stem cell-based therapies may offer new therapeutic avenues for lung diseases that currently lack efficient treatments. [Am J Respir Crit Care Med]

Effects of Extracellular Matrix on Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells into Smooth Muscle Cell Lineage: Utility for Cardiovascular Tissue Engineering
Results suggest that the signal transduction of the cell-matrix interaction for the differentiation of human Mesenchymal stem cells into smooth muscle cells was activated when cultured with laminin. [Cells Tissues Organs]

Use of Adipose Stem Cells and Polylactide Discs for Tissue Engineering of the Temporomandibular Joint Disc
The combination of adipose stem cells (ASCs) and fabricated bilayer biodegradable polylactide (PLA) discs has potential for the development of a tissue-engineered TMJ disc replacement. [J R Soc Interface]

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Cytori Completes Enrollment in International Breast Cancer Reconstruction Study; Interim Data to be Presented Dec. 12 at San Antonio Breast Cancer Symposium
The study is evaluating the use of cell-enriched fat grafting to restore functional and cosmetic deformities in women who have undergone partial mastectomy for early breast cancer.

Large Companies Still Looking for Acquisition Targets, Says Cutting Edge Information
In the past year, drug makers' thirst for innovation combined with small companies' dwindling operating capital to drive merger and acquisition activity. At the high end of the scale, consolidation among industry leaders created some of the richest pharmaceutical mergers in history.

EVENTS

Stem Cells World Congress
January 19-20, 2010
San Francisco, United States

Molecular Tri Conference & The Stem Cell Meeting
February 3-5, 2010
San Francisco, United States

2010 Bone Marrow Transplant Tandem Meetings
February 24-28, 2010
Orlando, United States

World Congress Regenerative Medicine
March 12-14, 2010
Bangkok, Thailand

The European Group for Blood & Marrow Transplantation Annual Meeting
March 21-24, 2010
Vienna, Austria

9th Transgenic Technology Meeting
March 22-24, 2010
Berlin, Germany

4th UK Mesenchymal Stem Cell Meeting
Leeds, United Kingdom
April 14, 2010

American Society of Clinical Oncology Annual Meeting
June 4-8, 2010
Chicago, United States

16th Annual ISCT meeting
May 23-26, 2010
Philadelphia, United States

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