Embryonic Stem Cell News 4.39, September 30, 2009. Click here if you are unable to see images in this e-mail.


TOP STORIES

Stem Cell Success Points to Way to Regenerate Parathyroid Glands
The scientists in this study were able to induce embryonic stem cells to differentiate into parathyroid cells that produced a hormone essential to maintaining bone density. [University of Michigan, Ann Arbor] 

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SCIENCE NEWS

Complimentary Webinar: Characterization of Mesenchymal Stem Cells in a Novel Serum- and Animal Component-Free Medium (MesenCult(R)-ACF)

Snorting Can Deliver Cells to the Brain
Researchers have shown that when stem cells suspended in fluid are snorted, they rapidly migrate into the brain.
[University of Minnesota, Minneapolis]

Stem Cells Point to Space Illness
Stem cells exposed to microgravity express different proteins than those grown in normal gravity, say Australian researchers.
[University of New South Wales, Sydney]

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CURRENT PUBLICATIONS

Microwell-mediated Control of Embryoid Body Size Regulates Embryonic Stem Cell Fate via Differential Expression of WNT5a and WNT11
In this study, the researchers used microengineered hydrogel microwells to direct ES cell differentiation and determined the role of WNT signaling pathway in directing the differentiation. [PNAS]

Modelling the Evolution of Culture Adapted Human Embryonic Stem Cells
The researchers here constructed a Monte Carlo simulation model to predict how changes in evolutionary factors can influence the appearance and spread of mutant embryonic stem cells, and verified its applicability by comparison with in vitro data. [Stem Cell Res]

Dazl Promotes Germ Cell Differentiation from Embryonic Stem Cells
This study describes a transgene expression approach to derive germ cells directly from embryonic stem cells in vitro without embryoid bodies formation. [J Mol Cell Biol]

Propensity of Human Embryonic Stem Cell Lines During Early Stage of Lineage Specification Controls Their Terminal Differentiation into Mature Cell Types
This study compared the developmental competences of two hESC lines (HUES-9 and HUES-7) at molecular, cellular and functional levels, upon spontaneous differentiation without any added inducing agents. [Exp Biol Med]

Reduced Differentiation Efficiency of Murine Embryonic Stem Cells in Stirred Suspension Bioreactors
The puerpose of this study was to use stirred-suspension bioreactors to expand and differentiate ESCs into osteogenic and chondrogenic cell types, and to explore if these ESC-derived cells influenced skeletal healing in an in vivo fracture model. [Stem Cells Dev]

Repopulation Efficiencies of Adult Hepatocytes, Fetal Liver Progenitor Cells, and Embryonic Stem Cell-Derived Hepatic Cells in Albumin-Promoter-Enhancer Urokinase-Type Plasminogen Activator Mice
This study attempted to assess the relative capacity of fetal liver progenitor cell suspensions and hepatic precursor cells derived from embryonic stem cells to engraft and repopulate a recipient liver compared with adult hepatocytes. [Am J Cardiovasc Pathol]

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INDUSTRY NEWS

Stem Cell Therapy International, Inc. Announces Merger With Histostem and Launching of AmStem International, Inc.
Terms of the deal called for Stem Cell Therapy to acquire a 90 percent controlling interest in the securities of Histostem, and for Histostem to acquire a 60% controlling interest in the securities of Stem Cell Therapy.

Southwest Michigan First Life Science Fund invests in RealBio Technology
The Southwest Michigan First Life Science Fund has announced RealBio Technology Inc. as the most recent addition to its portfolio.

Buying Binge Hits Biotech Firms
That appears to be the new mantra for the Massachusetts life sciences industry, where the strengthening economy and rising stock market have sparked a small wave of acquisitions.

Johns Hopkins Passes $100 Million Mark in Stimulus Funds
The Johns Hopkins University has won 250 research grants, totaling $114 million, through provisions in the federal stimulus package designed to advance scientific and medical knowledge while jump-starting the U.S. economy.

Pitt Researchers Net $5 Million from NIH to Explore Better Ways to Grow Cells for Regenerative Medicine
Regenerative medicine researchers at the University of Pittsburgh received two grants totaling more than $5 million from the National Institutes of Health to explore new methods for cultivating replacement cells from existing tissues and organs.




POLICY NEWS

FOOD AND DRUG ADMINISTRATION (United States)

Von Eschenbach Takes New Job - Trying to Overhaul FDA
Former FDA Commissioner Andrew von Eschenbach has joined Newt Gingrich's health think tank, the Center for Health Transformation, as an adviser.

November 16-17, 2009 Blood Products Advisory Committee Meeting Anncouncement

2009 Meeting Materials of the Blood Products Advisory Committee

THERAPEUTICS GOODS ADMINISTRATION (Australia)

Presentations About the Regulation of Blood and Tissues




EVENTS

World Stem Cells & Regenerative Medicine Congress Asia
October 5-7, 2009
Singapore

WiCell Human Embryonic Stem Cell Course
December 7-9, 2009
Madison, United States

49th American Society for Cell Biology Annual Meeting
December 5-9, 2009
San Diego, United States

Stem Cells and Regenerative Medicine World Congress
January 20-21, 2010
San Francisco, United States

Phacilitate Cell and Gene Therapy
January 25-27, 2010
Washington DC, United States

Molecular Medicine Tri-Conference 2010
February 3-5, 2010
San Francisco, United States

SMi's 2nd Annual Stem Cells
February 15-16, 2010
London, United Kingdom

Keystone Symposium B4 Stem Cell Differentiation and Dedifferentiation
February 15 - 20, 2010
Keystone, United States

Stem Cell Summit
February 16, 2010
New York, United States

ISSCR 8th Annual Meeting
June 16-19, 2010
San Francisco, United States



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