Embryonic Stem Cell News 4.37, September 16, 2009. Click here if you are unable to see images in this e-mail.


TOP STORIES

How Stem Cells Make Skin
Scientists have discovered two proteins that control when and how a layer of cells at the base of the skin containing stem cells switch to being skin cells. [European Molecular Biology Laboratory, Monterotondo]

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SCIENCE NEWS

Complimentary Webinar: Characterization of Mesenchymal Stem Cells in a Novel Serum- and Animal Component-Free Medium (MesenCult(R)-ACF)

STEMCELL Technologies Applauds Feeder-free Derivation of Human Induced Pluripotent Stem Cells
Using adipose cells as the starting cell population and mTeSR(TM)1, a defined medium that allows the expansion of human embryonic and induced pluripotent stem cells without the use of feeders, the researchers were able to fully reprogram cells to the pluripotent state. [STEMCELL Technologies, Vancouver]

Sculpting Cells with Light
The power to manipulate cells at will comes courtesy of a new genetically encoded switch that lets researchers use light to control a cell's shape and movement. [Howard Hughes Medical Institute, Chevy Chase]

Cytori Reports Preclinical Results that Suggest Adipose-Derived Regenerative Cells may Reverse Periodontal Disease
Cytori Therapeutics reported results from their preclinical study on the use of uncultured adipose-derived regenerative cells in the treatment of critical periodontal defects in a rat model. [Cytori Therapeutics, San Diego]

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*Sun et al., PNAS, 2009 STEMCELL Technologies Inc


 



CURRENT PUBLICATIONS

Zfp206, Oct4 and Sox2 are Integrated Components of a Transcriptional Regulatory Network in Embryonic Stem Cells
Presented here are data showing that Zfp206, a gene encoding a zinc-finger transcription factor, works together with two other transcription factors, Oct4 and Sox2, which are also essential regulators of ESC pluripotency. [J Biol Chem]

Cdk2 Inhibition Prolongs G1 Phase Progression in Mouse Embryonic Stem Cells
In this study, the scientists investigated the effects of downregulation of Cdk2 activity by olomoucine II in two mouse embryonic stem cells lines. [Stem Cells Dev]

PiggyBac Transposon-mediated, Reversible Gene Transfer in Human Embryonic Stem Cells
The researchers here used an optimized piggyBac transposon system, a non-viral system that efficiently mutagenizes and mediates gene transfer, to mediate gene transfer and expression of a bi-functional fluorescent reporter in human embryonic stem cells. [Stem Cells Dev]

Naturally Immortalized Mouse Embryonic Fibroblast Lines Support Human Embryonic Stem Cell Growth
This paper reports the derivation of three new mouse embryonic fibroblast cell lines, MEFLU-M, MEFLU-T, and MEFLU-TB, with different properties regarding growth and support for undifferentiated hESCs. [Cloning and Stem Cells]

Efficient Generation of Hepatocyte-like Cells from Human Induced Pluripotent Stem Cells
In this report, human iPS cells were induced to differentiate into hepatic cells by a stepwise protocol. [Cell Res]

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INDUSTRY NEWS

Connexon Creative Launches Mesenchymal Cell News
Mesenchymal Cell News is a free, weekly e-newsletter that keeps the mesenchymal cell community informed by providing the latest news from all areas of the field, including its science, policy, and business.

ReNeuron Signs Manufacturing Contract for Second-generation CTX Stem Cell Product
ReNeuron Group plc recently announced that it has signed a contract with Angel Biotechnology Holdings plc, under which Angel will manufacture clinical-grade lots of a second-generation formulation of ReNeuron's lead CTX stem cell line, for subsequent pre-clinical and clinical applications.

SEC Charges Seattle-Area Biotech Company with Fraudulently Hyping Stem Cell Breakthrough
The Securities and Exchange Commission recently charged a Bothell, Wash.-based biotechnology company, its former CEO, and its former Chief Scientific Officer for falsely telling investors that the company's stem cell technology had been proven successful and was headed for human trials.



POLICY NEWS

Legislature Approves Stem Cell and Biotechnology Education Bill
A bill to help California develop a homegrown workforce for the state's stem cell and biotechnology industries cleared its final hurdle in the legislature recently with Senate approval of amendments the Assembly adopted Tuesday.



EVENTS

World Stem Cell Summit 2009
September 23-25, 2009
Baltimore, United States

World Stem Cells & Regenerative Medicine Congress Asia
October 5-7, 2009
Singapore

49th American Society for Cell Biology Annual Meeting
December 5-9, 2009
San Diego, United States

Stem Cells and Regenerative Medicine World Congress
January 20-21, 2010
San Francisco, United States

Phacilitate Cell and Gene Therapy
January 25-27, 2010
Washington DC, United States

Molecular Medicine Tri-Conference 2010
February 3-5, 2010
San Francisco, United States

SMi's 2nd Annual Stem Cells
February 15-16, 2010
London, United Kingdom

Stem Cell Summit
February 16, 2010
New York, United States

ISSCR 8th Annual Meeting
June 16-19, 2010
San Francisco, United States


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