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Stem Cell Transplant in Mouse Embryo Yields Heart Protection in Adulthood
Stem cells play a role in heart muscle rejuvenation by attracting cells from the body that develop into heart muscle cells.



SCIENCE

Embryo's Heartbeat Drives Generation of New Blood Cells
Howard Hughes Medical Institute investigators have found that the blood's movement through the aorta triggers the production of new blood stem cells, which will give rise to all the red and white blood cells the organism needs to survive.

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ABSTRACTS

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Analysis of the Factors that Limit the Ability of Feeder Cells to Maintain the Undifferentiated State of Human Embryonic Stem Cells
Objectives of this study were to determine whether timing between mouse embryonic fibroblasts inactivation and their use as feeder cell layer influenced hESC growth and differentiation, and to begin defining the mechanism(s) involved.

Adipocyte Differentiation in Human Embryonic Stem Cells Transduced With Oct4 shRNA Lentivirus
This study generated HES2 and HES3 hESC lines stably transduced with lentivirus carrying Oct4 short hairpin RNA (shRNA) that display 80-90% reduction of Oct4 expression.

The Pluripotency-Associated Gene Dppa4 Is Dispensable for Embryonic Stem Cell Identity and Germ Cell Development but Essential for Embryogenesis
To rigorously assess Dppa4's suggested roles in pluripotent cells, this study generated Dppa4-deficient and Dppa4/Dppa2 doubly deficient ES cells, as well as mice lacking Dppa4.

mTOR Supports Long-term Self-renewal and Suppresses Mesoderm and Endoderm Activities of Human Embryonic Stem Cells
This study demonstrates an essential role for the serine/threonine protein kinase mammalian target of rapamycin in regulating hESC long-term undifferentiated growth.

Noninvasive Monitoring of Embryonic Stem Cells In Vivo with MRI Transgene Reporter
Reporter gene-based magnetic resonance imaging offers unique insights into behavior of cells after transplantation, which could significantly benefit stem cell research and translation.



INDUSTRY

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Connexon Creative Launches Mammary Cell News
Mammary Cell News is a weekly e-newsletter that keeps members of the mammary cell community informed by providing the latest news from all areas of the field, including its science, research and business.
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STEMSOFT Software Inc. Licenses StemLab Software to Carter BloodCare
STEMSOFT Software Inc, the leading provider software solutions for cell therapy transplant, is pleased to announce the licensing of StemLab, the leading cell therapy and cord blood banking laboratory software, to Carter BloodCare's Stem Cell Transplant Laboratory in Bedford, TX.

Advanced Cell Technology Provides Single Blastomere Technology To CHA Bio & Diostech Co., Ltd.
Advanced Cell Technology, Inc. and CHA Bio & Diostech Co., Ltd. announced recently that the parties have entered into a licensing agreement under which Advanced Cell will license its proprietary "single blastomere technology," to CHA Bio for development and commercialization exclusively in Korea.

UC Davis Opens Horse Stem Cell Lab
The Regenerative Medicine Laboratory at the William R. Pritchard Veterinary Medical Teaching Hospital allows for processing, culturing and storing stem cells for horses.

Maryland Stem Cell Research Commission Announces 59 Projects for Funding
The Maryland Stem Cell Research Commission has completed its evaluation of the 147 applications in response to its three official Requests for Applications.

Lonza Expands Cell Therapy Business with New Facility in Singapore
Lonza Group Ltd is expanding its Cell Therapy business with the construction of a new facility in Singapore.

China to Invest $9.2 Bln in New Technology
China will spend 62.8 billion Yuan ($9.2 billion) this year and the next on new technology as part of its efforts to stimulate economic growth, the State Council said on Wednesday.

Fate Therapeutics Granted Exclusive License for Stem Cell Modulators by Children's Hospital Boston and Massachusetts General Hospital
Fate Therapeutics, Inc. announced recently that it has acquired exclusive intellectual property rights jointly owned by Children's Hospital Boston and Massachusetts General Hospital.

NeoStem Obtains Exclusive License to Innovative Stem Cell Procedure Treating Musculoskeletal Diseases
NeoStem, Inc. announced recently it has signed an exclusive royalty-bearing license agreement for the Asia territory to use an innovative process that rapidly grows a patient's own adult stem cells to treat a variety of musculoskeletal diseases.

Stem Cell Patent Digests
The UKNSCN has embarked upon a pilot project to provide the community with regular digests of both published and granted patents in the stem cell field.

Novocell Awarded Patent for Innovative Stem Cell Therapy for Diabetes
Novocell, Inc. recently announced that it has received U.S. Patent No. 7,534,608 with method claims covering the Company's innovative stem cell therapy for the production of functional pancreatic, insulin producing cells from human embryonic stem cells.

U.S. Patent Office Upholds StemCells' Patents - Company Moves to Resume Patent Infringement Cases Against Neuralstem
StemCells, Inc. announced recently that the U.S. Patent and Trademark Office has upheld the validity of the remaining two neural stem cell patents which were subjected to reexamination proceedings commenced by Neuralstem, Inc.

Stem Cell Therapeutics Announces Issuance of Additional US Patent for Use of Prolactin
Stem Cell Therapeutics Corp. has been issued United States Patent No. 7,534,765 covering methods of using of prolactin for enhancing the formation of oligodendendrocytes in vivo.



POLICY

STEMSOFT Software Inc. Releases White Paper on Electronic Records in Cell Therapy - Regulatory and Accreditation Requirements

Bush Bioethics Advisors Take Potshot at Obama Stem Cell Platform
Prestigious Hastings Center bioethics think tank publishes comments by more than half of President Bush's bioethics council.

Obama Talks of Common Ground Amid Notre Dame Protests
Amid protests over his positions on abortion and embryonic stem-cell research, President Obama spoke to graduates at the University of Notre Dame about coming together over disagreements by finding "common ground."

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