BMP4 Induces Primitive Endoderm but not Trophectoderm in Monkey Embryonic Stem Cells
This paper suggests that BMP4 induced differentiation into the primitive endoderm lineage but not into trophoblast in monkey embryonic stem cells.
Cells Derived from Human Umbilical Cord Blood Support the Long-Term Growth of Undifferentiated Human Embryonic Stem Cells
This study reports the successful culture of two hESC lines (H1 and H9) on human umbilical cord blood-derived fibroblast-like cells.
Role of Nitric Oxide Signaling Components in Differentiation of Embryonic Stem Cells into Myocardial Cells
The researchers demonstrate the effect of nitric oxide donors and soluble guanylyl cyclase activators in differentiation of embryonic stem cells into myocardial cells.
Generation of Cardiomyocytes from New Human Embryonic Stem Cell Lines Derived from Poor-quality Blastocysts
This study shows that hES cell lines can be obtained from poor-quality blastocysts with the same efficiency as that obtained from good- or intermediate-quality blastocysts.
Human Embryonic Stem Cell-Derived Motor Neurons are Sensitive to the Toxic Effect of Glial Cells Carrying an ALS-Causing Mutation
The researchers ask whether specific neuronal subtypes produced from human embryonic stem cells can be used to investigate the mechanisms leading to neural degeneration in amyotrophic lateral sclerosis.
Non-Cell-Autonomous Effect of Human SOD1G37R Astrocytes on Motor Neurons Derived from Human Embryonic Stem Cells
To uncover the contribution of astrocytes to human motor neuron degeneration, the researchers co-cultured hESC-derived motor neurons with human primary astrocytes expressing mutated SOD1.
