Japanese Researchers Make Brain Tissues from Stem Cells
Japanese researchers said Thursday they had created functioning human brain tissues from stem cells, a world first that has raised new hopes for the treatment of disease.

Scientists Confirm a Molecular Clipping Mechanism Behind Stem Cell Development
New research from Rockefeller University scientists now shows that during specific stages of differentiation in mouse embryonic stem cells, crucial marks can be removed by cutting off the end of the histone's tail.

Stanford Research Sheds Light on Key Trigger of Embryonic Stem Cell Differentiation
Researchers have found that embryoid bodies have hallmarks of gastrulation and that this process is initiated by a single signaling pathway in embryoid bodies and in real embryos.

Generation of T Lineage Cells from Human Embryonic Stem Cells in a Feeder Free System
In this report, the researchers show that T cell progenitors can be derived from hESC cultured as embryoid bodies and that they give rise to phenotypically and functionally normal cells of the T lineage when transferred into human thymic tissue implanted in immunocompromised mice.

De Novo DNA Methylation Promoted by G9a Prevents Reprogramming of Embryonically Silenced Genes
The pluripotency-determining gene Oct3/4 (also called Pou5f1) undergoes postimplantation silencing in a process mediated by the histone methyltransferase G9a.

Role of NKG2D-ligands and ICAM-1 in NK cell-mediated Lysis of Murine Embryonic Stem Cells and Embryonic Stem Cell-derived Cardiomyocytes
The reseachers in this study characterized embryonic stem cell-derived cardiomyocytes in terms of their sensitivity to natural killer cells, whose immune rejection hamper ES cells' clinical application.

Knockdown of the Co-chaperone Hop Promotes Extranuclear Accumulation of Stat3 in Mouse Embryonic Stem Cells
A key event in the mechanism of mouse embryonic stem cell pluripotency is phosphorylation, dimerisation and translocation to the nucleus of the signal transducer and activator of transcription3, Stat3.

Osiris Leads Stem Cell Field as First Company to Turn Profit
Osiris Therapeutics Inc. became the first developer of stem cell therapies to turn a profit after selling an implantable stem-cell product used in fractures to another company and earning $5.3 million in the third quarter.

BioLife Solutions to Supply CryoStor(TM) to Cryobanks International as Standard Media for Preservation and Storage of Umbilical Cord Blood Stem Cells
BioLife Solutions Inc. recently announced that it will supply its CryoStor biopreservative freezing media to Cryobanks International for long-term storage of stem cells isolated from umbilical cord blood.

Michigan Voters Approve Stem Cell Research Measure
Michigan voters on Tuesday approved Proposal 2, which changes state law to allow people to donate embryos left over from fertility treatments for scientific research.

Stem Cell Supporters Await Their Obama Moment
Stem cell advocates and researchers are eagerly awaiting the moment next year when president-elect Barack Obama rescinds a directive that limits federal funding of human embryonic stem-cell research.