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ETV6-PDGFRB and FIP1L1-PDGFRA Stimulate Human Hematopoietic Progenitor Proliferation and Differentiation into Eosinophils: Role of NF-κB
Researchers introduced ETV6-PDGFRB and FIP1L1-PDGFRA in human CD34+ hematopoietic progenitors and stem cells isolated from umbilical cord blood. [Haematologica] Abstract
Cord Blood Stem Cell-Derived DCs Generate Potent Antigen-Specific Immune Responses and Anti-Tumor Effects
This study aims to evaluate if cord blood stem cells can be new source of dendritic cells (DCs) which can generate more potent antigen-specific immune responses and anti-tumor effects. [Clin Sci] Abstract
Endothelial Progenitor Cells (EPCs) as Gene Carrier System for Rat Model of Human Glioma
The purposes of this study were to investigate whether intravenously administered, genetically transformed cord blood derived EPCs can carry human sodium iodide symporter to the sites of tumors in rat orthotopic model of human glioma and express transgene products, and whether accumulation of these administered EPCs can be tracked by different in vivo imaging modalities. [PLoS One] Abstract
Bioadhesive Control of Plasma Proteins and Blood Cells from Umbilical Cord Blood onto the Interface Grafted with Zwitterionic Polymer Brushes
In this work, bioadhesive behavior of plasma proteins and blood cells from umbilical cord blood onto a zwitterionic poly(sulfobetaine methacrylate) polymer brushes was studied. [Langmuir] Abstract
Isolation, Characterization and Differentiation of Mesenchymal Stem Cells from Amniotic Fluid, Cord Blood and Wharton's Jelly in the Horse
This work aimed to identify and characterize stem cells from equine amniotic fluid, cord blood and Wharton's jelly. [Reproduction] Abstract
Mesenchymal Stromal Cells Derived from Umbilical Cord Blood Migrate in Response to Complement C1q
Researchers found that complement component 1 subcomponent q (C1q) chemoattracted human umbilical cord blood-derived mesenchymal stromal cells (MSC) in a dose-dependent manner and that the receptor for the global domains of C1q is present on the surface of MSC. [Cytotherapy] Abstract
Hypoxia Improves Expansion Potential of Human Cord Blood-Derived Hematopoietic Stem Cells and Marrow Repopulation Efficiency
The objective of this investigation was to compare cellular, functional and molecular responses of human umbilical cord blood-derived hematopoietic stem and progenitor cells in culture under hypoxic and normoxic conditions. [Eur J Haematol] Abstract
Inhibition of p38 MAPK Activity Promotes Ex Vivo Expansion of Human Cord Blood Hematopoietic Stem Cells
Investigators examined the effect of inhibition of p38 mitogen-activated protein kinase (p38) on the expansion of human umbilical cord blood CD133+ cells because activation of p38 has been implicated in the induction of hematopoietic stem cell senescence under various physiological and pathological conditions. [Ann Hematol] Abstract
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